SARS-CoV-2 S1 Protein RBD (L452R Mutation) | abx160087

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abx160087
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1 mg
  • SARS-CoV-2 S1 Protein RBD (L452R Mutation)
  • SARS-CoV-2 S1 Protein RBD (L452R Mutation)
£2,212.78
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Description

SARS-CoV-2 S1 Protein RBD (L452R Mutation). Cat# abx160087. Supplier: abbexa.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike S1 Protein Receptor-Binding Domain (RBD) is a recombinant protein expressed in Insect cells.

The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

The L452R mutation is present in the B.1.429/B.1.427 (CAL.20C/Epsilon) variants first identified in California, USA.

Target Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) S1 Protein RBD (L452R Mutation)
Target Modification Leu452Arg
Modification Mutation
Origin Virus
Expression Recombinant
Tested Applications ELISA, WB
Host Insect
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Form Liquid
Purity ≥ 90% (SDS-PAGE)
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 26 kDa
Observed MW (12% reducing SDS-PAGE): ~28 kDa
Sequence Fragment 319-541 AA.
Tag C-terminal His tag
Buffer PBS, pH 7.4. Does not contain preservatives.
Concentration 2.2 mg/ml
Directions for use Centrifuge before opening to ensure complete recovery of vial contents.
Availability Shipped within 5-10 working days.
Note This product is for research use only. This product is shipped with dry ice.
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