SARS-CoV-2 S1 Protein RBD (L452R Mutation) | abx160087
- Usually shipped in 5 working days
- 1 mg
SARS-CoV-2 S1 Protein RBD (L452R Mutation). Cat# abx160087. Supplier: abbexa.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike S1 Protein Receptor-Binding Domain (RBD) is a recombinant protein expressed in Insect cells.
The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
The L452R mutation is present in the B.1.429/B.1.427 (CAL.20C/Epsilon) variants first identified in California, USA.
|Target||Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) S1 Protein RBD (L452R Mutation)|
|Tested Applications||ELISA, WB|
|Recommended dilutions||Optimal dilutions/concentrations should be determined by the end user.|
|Purity||≥ 90% (SDS-PAGE)|
|Purification||Purified by affinity chromatography.|
|Storage||Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.|
|Molecular Weight||Calculated MW: 26 kDa
Observed MW (12% reducing SDS-PAGE): ~28 kDa
|Sequence Fragment||319-541 AA.|
|Tag||C-terminal His tag|
|Buffer||PBS, pH 7.4. Does not contain preservatives.|
|Directions for use||Centrifuge before opening to ensure complete recovery of vial contents.|
|Availability||Shipped within 5-10 working days.|
|Note||This product is for research use only. This product is shipped with dry ice.|