Gain insight into the behavior of the SARS-CoV-2 spike protein that has three key receptor binding domain mutations found in B.1.351—K417N, E484K, N501Y.
Based on SBI’s popular and highly cited pPACKH1 Packaging System
Uses codon-optimized SARS-CoV-2 K417N, E484K, N501Y “S” protein in place of VSV-G envelope protein
Ideal for vaccine and antiviral efficacy studies under BSL2 conditions
Package any 3rd-generation lentivector reporter of your choice, including SBI’s popular LentiLabeler reporters
Compare with our full range of pPACK-SPIKE S protein pseudotyped lentiviruses to better understand emerging variants
Use with pPACK-BALD™, an envelope protein-free lentivector packaging system that is an ideal negative control