SARS-CoV-2 Spike Glycoprotein Antibody | abx376478
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SARS-CoV-2 Spike Glycoprotein Antibody. Cat# abx376478. Supplier: abbexa.
SARS-CoV-2/COVID-19 Spike Glycoprotein Antibody is a chimaeric recombinant Monoclonal antibody expressed in CHO cells against SARS-CoV-2 Spike Glycoprotein, containing Mouse variable region and Human IgG1 Kappa constant region.
The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
|Target||Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein|
|Tested Applications||ELISA, WB|
|Recommended dilutions||ELISA: 1/5000 - 1/10000, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.|
|Immunogen||Recombinant SARS-CoV-2 S1 protein.|
|Purification||Purified by affinity chromatography.|
|Storage||Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.|
|Buffer||PBS, pH 7.5.|
|Availability||Shipped within 10-20 working days.|
|Note||This product is for research use only.|