abbexa
SARS-CoV-2 Spike Glycoprotein Antibody | abx243126
- SKU:
- abx243126
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- Availability:
- Usually shipped in 5 working days
Description
SARS-CoV-2 Spike Glycoprotein Antibody. Cat# abx243126. Supplier: abbexa.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Glycoprotein Antibody is a chimaeric recombinant antibody expressed in HEK293 cells for the detection of SARS-CoV-2/COVID-19 S Protein. This antibody contains Mouse scFv and C-terminal Human IgG1 Fc tag.
The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
Target | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein |
Clonality | Monoclonal |
Reactivity | Virus |
Origin | Human |
Expression | Recombinant |
Tested Applications | ELISA, LF |
Host | Human, Mouse |
Recommended dilutions | ELISA: 1/10,000 - 1/50,000, LF (Gold Immunochromatography): 1/500 - 1/5,000, Neutralization: 1/50 - 1/10,000. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | Recombinant SARS-CoV-2 S protein (16-685 AA) expressed in Mammalian cells |
Isotype | IgG1 |
Form | Liquid |
Purification | Purified by affinity chromatography. |
Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | P0DTC2 (UniProt, ExPASy) |
GeneID | 43740568 |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |
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