SARS-CoV-2 E Protein Polyclonal Antibody (2019-nCoV) | E-AB-V1033

SARS-CoV-2 E Protein Polyclonal Antibody (2019-nCoV) | E-AB-V1033 | Elabscience

Category Type: Polyclonal

Synonyms: 2019-nCoV E protein, 2019-nCoV sM protein, Envelope small membrane protein

Applications: ELISA

Reactivity: SARS-COV2

Host: Rabbit

Isotype: IgG

Concentration: 0.30mg/ml

Purify Method: Produced in rabbits immunized with purified, Recombinant SARS-CoV-2 E protein

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Buffer: PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.

Dilution: Elisa:1:4000~1:8000

Clone NO: N/A

Conjugation: Unconjugated

Immunogen Cat: N/A

Immunogen : Recombinant SARS-CoV-2 E protein (Met1-Val75)

Background: Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.