SARS-CoV-2 S2 Protein Polyclonal Antibody (2019-nCoV) | E-AB-V1032
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SARS-CoV-2 S2 Protein Polyclonal Antibody (2019-nCoV) | E-AB-V1032 | Elabscience
Category Type: Polyclonal
Synonyms: Spike glycoprotein, E2, Peplomer protein, Spike protein S2, S
Purify Method: Produced in rabbits immunized with purified, Recombinant SARS-CoV-2 S2 Protein
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Clone NO: N/A
Immunogen Cat: N/A
Immunogen : Recombinant SARS-CoV-2 S2 Protein (Ser686-Pro1213)
Background: Mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.