SARS-CoV-2 Spike Glycoprotein RBD Nanobody | abx243130
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SARS-CoV-2 Spike Glycoprotein RBD Nanobody. Cat# abx243130. Supplier: abbexa.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Glycoprotein Receptor-Binding Domain Protein Nanobody is a recombinant monoclonal antibody expressed in HEK293 cells for the detection of SARS-CoV-2/COVID-19 S RBD Protein. This antibody contains VHH fused with Human IgG1 Fc at the C-terminus.
The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
|Target||Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein|
|Tested Applications||ELISA, LF|
|Recommended dilutions||ELISA: 1/10,000 - 1/100,000, LF (Gold Immunochromatography): 1/10,000 - 1/40,000, Neutralization: 1/100 - 1/10,000. Optimal dilutions/concentrations should be determined by the end user.|
|Immunogen||abx600065 - Recombinant SARS-CoV-2 S protein (319-514 AA) expressed in Mammalian cells.|
|Purification||Purified by affinity chromatography.|
|Storage||Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.|
|UniProt Primary AC||P0DTC2 (UniProt, ExPASy)|
|Buffer||0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.|
|Availability||Shipped within 5-10 working days.|
|Note||This product is for research use only.|