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SARS-CoV-2 Nucleocapsid Protein Antibody | abx243131

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SKU:: abx243131
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Description

Description

SARS-CoV-2 Nucleocapsid Protein Antibody. Cat# abx243131. Supplier: abbexa.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Nucleocapsid Protein Antibody is a chimaeric recombinant antibody expressed in HEK293 cells for the detection of SARS-CoV-2/COVID-19 NP. This antibody contains Mouse variable regions and Human IgG1 Kappa constant regions.

The SARS-CoV-2 Nucleoprotein (also known as Nucleocapsid Protein or N Protein) is a protein that binds to the RNA in the viral particle. Changes to two amino acids in the nucleoprotein are thought to contribute to the virus’ ability to infect humans; this mutation allows the virus to reduce the binding capability of an HLA-C allele found in many Europeans. The nucleoprotein is the second most-common protein in SARS-CoV-2 targeted by the immune system, after the spike protein.

Target	Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Nucleocapsid Protein
Clonality	Monoclonal
Reactivity	Virus
Origin	Human
Expression	Recombinant
Tested Applications	ELISA, LF
Host	Human, Mouse
Recommended dilutions	ELISA: 1/10,000 - 1/50,000, WB: 1/500 - 1/5,000, LF (Gold Immunochromatography): 1/500 - 1/2,000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	abx600062 - Recombinant SARS-CoV-2 Nucleoprotein (1-419 AA) expressed in Mammalian cells
Isotype	IgG₁ Kappa
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P0DTC9 (UniProt, ExPASy)
GeneID	43740575
Buffer	0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.