SARS-CoV-2 NSP8 Polyclonal Antibody (2019-nCoV) | E-AB-V1041

SARS-CoV-2 NSP8 Polyclonal Antibody (2019-nCoV) | E-AB-V1041 | Elabscience

Category Type: Polyclonal

Synonyms: Non-structural protein 8, Replicase polyprotein 1a

Applications: ELISA

Reactivity: SARS-COV2

Host: Rabbit

Isotype: IgG

Concentration: 0.93mg/ml

Purify Method: Produced in rabbits immunized with purified, Recombinant SARS-CoV-2 NSP8

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Buffer: PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.

Dilution: Elisa:1:4000~1:8000

Clone NO: N/A

Conjugation: Unconjugated

Immunogen Cat: N/A

Immunogen : Recombinant SARS-CoV-2 NSP8 (A3943-Q4118)

Background: Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.