Elabscience
Recombinant SARS-CoV-2 S Protein HR1 (N-6His-Sumo) | 763-PKSV030305
- SKU:
- 763-PKSV030305
- UPC:
- MPN:
- Availability:
- IN STOCK
Description
Recombinant SARS-CoV-2 S Protein HR1 (N-6His-Sumo) | PKSV030305 | Elabscience.
Synonym: SARS-CoV-2 Spike; SARS-CoV-2 Spike Protein
Activity: Test in progress
Protein Construction: Recombinant 2019-nCoV S protein HR1 Protein is produced by our E.coli expression system and the target gene encoding Gly910-Glu988 is expressed with a 6His, Sumo tag at the N-terminus.
Sequence: Gly910-Glu988
Fusion tag: N-6His-Sumo
Accession: QHD43416.1
Species: SARS-CoV-2
Expressed Host: E.coli
Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Mol Mass: 20.8kDa
AP Mol Mass: 25kDa
Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Reconstitution: Not Applicable
Background: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS) . The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD) , which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. After binding of RBD in S1 subunit of S protein on the virion to the ACE2 receptor on the target cell, the heptad repeat 1 (HR1) and 2 (HR2) domains in its S2 subunit of S protein interact with each other to form a six-helix bundle (6-HB) fusion core, bringing viral and cellular membranes into close proximity for fusion and infection. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Related Products

Recombinant SARS-CoV-2 S Protein HR1 | 763-PKSV030306
Elabscience

Recombinant SARS-CoV-2 N Protein biotinylated (N-6His-Avi) (Active) | 763-PKSV030311
Elabscience

Recombinant SARS-CoV-2 S-trimer Protein | 763-PKSV030322
Elabscience

Recombinant SARS-CoV-2 S-trimer 6P Protein | 763-PKSV030323
Elabscience

Recombinant SARS-CoV-2 S+E+M protein | 763-PKSV030324
Elabscience
Customers Also Viewed

Recombinant 2019-nCoV M Protein | 763-PKSV500000
Elabscience

Anti-SARS-CoV-2 Spike RBD (CB6 biosimilar) Neutralizing Antibody | E-AB-V1028
Elabscience

Anti-2019-nCoV S-IgA Neutralizing Antibody | E-AB-V1027
Elabscience

Anti-2019-nCoV S-IgM Neutralizing Antibody | E-AB-V1026
Elabscience

Recombinant SARS-CoV-2 Spike Protein (RBD, His Tag) (W436R) (Active) | 763-PKSV030469
Elabscience

Recombinant SARS-CoV-2 Spike RBD (N439K) (His Tag) | 763-PKSV030412
Elabscience

Recombinant SARS-CoV-2 S-stable trimer Protein (C-6His) (Active) | 763-PKSV030314
Elabscience

Recombinant SARS-CoV-2 N Protein biotinylated (N-6His-Avi) (Active) | 763-PKSV030311
Elabscience

Recombinant SARS-CoV-2 S Protein RBD (C-6His) V2 (Active) | 763-PKSV030308
Elabscience

Recombinant SARS-CoV-2 S Protein RBD (C-mFc) V2 (Active) | 763-PKSV030307
Elabscience

Recombinant SARS-CoV-2 S Protein HR1 | 763-PKSV030306
Elabscience

Sterile Viral Transport and Preservation Medium; Flat Bottom Tube (500 x 1 ml vials) | BSV-VTM-004
BioServUK

Sterile Viral Transport and Preservation Medium; Flat Bottom Tube (100 x 1 ml vials) | BSV-VTM-003
BioServUK

Sterile Viral Transport and Preservation Medium; Conical Bottom Tube (500 x 3 ml vials) | BSV-VTM-002
BioServUK

Sterile Viral Transport and Preservation Medium; Conical Bottom Tube (100 x 3 ml vials) | BSV-VTM-001
BioServUK

MRC Nasopharyngeal Flocked Swabs - 5,000 pcs | BSV-MSC-96000-5000
BioServUK

SARS-CoV-2 full-length Trimeric Spike Antigen MultiPack (7 Variants & Wild 1mg each) | BSV-COV-PR-MP-1
BioServUK

Assay Diluent (Buffered saline with protein stabilisers, surfactant and 0.1 g/L Thiomersal preservative) (500 ml) | R1-04
BioServUK

Coronavirus SARS-CoV-2 Spike RBD Protein, polyhistidine tag | LTP-V009-1mg
BioServUK

Healgen Rapid COVID-19 Antigen Self-Test | BSV-GCCOV-502a-H1-10
BioServUK

Elite Anti-SARS-CoV-2 Spike (S2) Monoclonal Antibody, Clone COS2α-1 | BSV-S2-01-0.1mg
BioServUK

Elite Anti-SARS-CoV-2 Spike (S1) Monoclonal Antibody, Clone COS1α | BSV-S1-01-0.1mg
BioServUK

Elite Anti-SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody, Clone CONε-5 | BSV-N-05-0.1mg
BioServUK

Elite Anti-SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody, Clone CONδ-4 | BSV-N-04-0.1mg
BioServUK

Elite Anti-SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody, Clone CONγ-3 | BSV-N-03-0.1mg
BioServUK

Elite Anti-SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody, Clone CONβ-2 | BSV-N-02-0.1mg
BioServUK

Elite Anti-SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody, Clone CONα-1 | BSV-N-01-0.1mg
BioServUK

Recombinant COVID-19 Omicron RBD (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H) protein, His-tagged
Creative BioMart

Recombinant COVID-19 Omicron RBD (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H) protein, His-Avi-tagged, Biotinylated
Creative BioMart

Recombinant COVID-19 Omicron RBD (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H) protein, His-tagged
Creative BioMart

Recombinant COVID-19 Omicron RBD (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H) protein, His-Avi-tagged, Biotinylated
Creative BioMart

SARS-CoV-2 (B.1.1.529/Omicron) Spike Glycoprotein (S1) RBD, His-Tag (HEK293)
The Native Antigen

abm | Sample Collection and Viral Transport Solution | G631
ABM Good

GENLISA™ SARS-CoV-2 (Covid-19) Beta Neutralizing Antibody (B.1.351, B.1.351.2,B.1.351.3) ELISA
Krishgen


SARS-CoV-2 S Protein RBD-SD1 | abx163966
abbexa


SARS-CoV-2 Nucleoprotein CTD Domain | abx163975
abbexa


SARS-CoV-2 Nucleoprotein NTD Domain | abx163974
abbexa


SARS-CoV-2 S1 Protein Antibody | abx226547
abbexa


SARS-CoV-2 Spike Glycoprotein Antibody | abx376478
abbexa


SARS-CoV-2 Spike Protein RBD (Delta B.1.617.2 Variant) Neutralizing Antibody | abx376487
abbexa
COVID-19 Viral Transport Media Special Kit
LaunchWorks
COVID-19 Viral Transport Media Standard Kit
LaunchWorks

COVID-19 Viral Transport Media Bulk Package Kit
LaunchWorks

COVID-19 Viral Transport Media 1L Filled Bottles
LaunchWorks

COVID-19 Viral Transport Media Filled Tubes
LaunchWorks

pPACK-BALD Envelope Protein-free Lentivector Packaging Mix (XL)
SBI System Biosciences

human-anti human IgM mAb (M1) | E42020TM1
EnoGene

Spike protein monoclonal antibody, HRP conjugated | CSB-RA33245B1GMY
Cusabio

Recombinant Human Novel Coronavirus Spike glycoprotein(S), partial | CSB-MP3324GMY1b1
Cusabio

Recombinant Human Novel Coronavirus Spike glycoprotein(S), partial | CSB-MP3324GMY1
Cusabio