Elabscience
Recombinant SARS-CoV-2 S+E+M protein | 763-PKSV030324
- SKU:
- 763-PKSV030324
- UPC:
- MPN:
- Availability:
- IN STOCK
Description
Recombinant SARS-CoV-2 S+E+M protein | PKSV030324 | Elabscience.
Synonym: Spike glycoprotein;Envelope small membrane protein, E protein;Membrane protein
Activity: Test in progress
Protein Construction: Recombinant SARS-CoV-2 S&M&E fusion is produced by E.coli expression system and the target gene encoding Arg319-Phe541&Arg38-Val75&Arg101-Gln222 is expressed with C-His Tag
Sequence: Arg319-Phe541&Arg38-Val75&Arg101-Gln222
Fusion tag: C-His
Accession: P0DTC2&P0DTC4&P0DTC5
Species: SARS-CoV-2
Expressed Host: E.coli
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: >90% as determined by SDS-PAGE
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass: N/A
AP Mol Mass: 44.7kDa
Formulation: Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
Reconstitution: Please refer to the printed manual for detailed information.
Background: Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS) . The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD) , which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Related Products

Recombinant SARS-CoV-2 S Protein HR1 | 763-PKSV030306
Elabscience

Recombinant SARS-CoV-2 S-trimer Protein | 763-PKSV030322
Elabscience

Recombinant SARS-CoV-2 S-trimer 6P Protein | 763-PKSV030323
Elabscience

Recombinant SARS-CoV-2 NSP15 protein | 763-PKSV030329
Elabscience

Recombinant SARS-CoV-2 ORF7a protein | 763-PKSV030331
Elabscience
Customers Also Viewed

SARS-CoV-2 Y14 | GEN-P0DTD3
Gentaur

SARS-CoV-2 M | GEN-P0DTC5
Gentaur

SARS-CoV-2 E | GEN-P0DTC4
Gentaur

SARS-CoV-2 N | GEN-P0DTC9
Gentaur

SARS-CoV-2 N | S-CP-P2009
Elabscience

SARS-CoV-2 M | S-CP-P2008
Elabscience

SARS-CoV-2 Spike Glycoprotein-crude | S-CP-P2007
Elabscience

SARS-CoV-2 Spike Glycoprotein-crude (B.1.1.529-Omicron) | S-CP-P2010
Elabscience

HCoV-229E Spike Glycoprotein | GEN-P15423
Gentaur

Recombinant SARS-CoV-2 NSP16 protein | 763-PKSV030330
Elabscience

Recombinant SARS-CoV-2 NSP12 protein | 763-PKSV030327
Elabscience

Recombinant SARS-CoV-2 S-trimer 6P Protein | 763-PKSV030323
Elabscience

Recombinant SARS-CoV-2 S-trimer Protein | 763-PKSV030322
Elabscience

CleanPlex SARS-CoV-2 Panel (384) | 918012
BioServUK

CleanPlex SARS-CoV-2 Panel (96) | 918011
BioServUK

CleanPlex SARS-CoV-2 Panel (8) | 918010
BioServUK

CleanPlex for MGI SARS-CoV-2 Panel (384) | 918003
BioServUK

Biotinylated Detection Affimer Reagent | BSV-COV-DET-05
BioServUK

Capture Affimer Reagent 2 | BSV-COV-CA03
BioServUK

Capture Affimer Reagent 1 | BSV-COV-CA01
BioServUK

SARS-CoV-2 (B.1.1.529/Omicron) Spike Glycoprotein (S1), His-Tag (CHO)
The Native Antigen


SARS-CoV-2 S1 Protein Antibody | abx229485
abbexa


SARS-CoV-2 Spike Glycoprotein Antibody | abx226551
abbexa


SARS-CoV-2 Spike Glycoprotein Antibody | abx243126
abbexa


SARS-CoV-2 Spike Glycoprotein Antibody | abx243125
abbexa


SARS-CoV-2 Spike Glycoprotein Antibody | abx376479
abbexa


SARS-CoV-2 Spike Glycoprotein RBD Antibody Pair | abx243136
abbexa

Biovision | Human CellExp™ SARS-CoV-2 Spike RBD (L452R, T478K), Recombinant | P1744
Biovision

Biovision | Human CellExp™ SARS-CoV-2 S1 Protein (Delta Plus), Recombinant | P1677
Biovision
xNetic™ Viral DNA/RNA Extraction Kit
LaunchWorks

Recombinant Human Novel Coronavirus Spike glycoprotein(S) | CSB-YP3324GMYa4
Cusabio

Recombinant Human Novel Coronavirus Spike glycoprotein(S), partial | CSB-YP3324GMY1
Cusabio

Recombinant Human Novel Coronavirus Spike glycoprotein(S), partial | CSB-MP3324GMY1b1
Cusabio

Recombinant Human Novel Coronavirus Spike glycoprotein(S), partial | CSB-MP3324GMY1
Cusabio

Recombinant Human Novel Coronavirus Spike glycoprotein(S), partial | CSB-MP3324GMY
Cusabio

pPACK-SPIKE™ Beta (B.1.351), SARS-CoV-2 "S" Pseudotype - Beta (B.1.351) Variant - Lentivector Packaging Mix (XL) | CVD19-645A-1
SBI System Biosciences

pPACK-SPIKE™ B.1.525, SARS-CoV-2 "S" Pseudotype - B.1.525 Variant - Lentivector Packaging Mix | CVD19-620A-1
SBI System Biosciences

HEK293 "N" SARS-CoV-2 Nucleocapsid Overexpression Stable Cell Line | CVD19-220A-1
SBI System Biosciences

SARS-CoV-2 Spike Glycoprotein Expression (S) Lentivector, pCDH-CMV-SARS-CoV-2-S-EF1α-Puro (Plasmid) | CVD19-130PA-1
SBI System Biosciences

SARS-CoV-2 S Recombinant Antibody, HRP Conjugated | A73673
EpiGentek

SARS-CoV-2 S Recombinant Antibody, FITC Conjugated | A73674
EpiGentek

SARS-CoV-2 S Recombinant Antibody | A73670
EpiGentek

Recombinant SARS-CoV-2 Spike S1 Protein with His-Tag | E80004
EpiGentek

Human CellExp™ Coronavirus Spike Protein (SARS-CoV-2), Recombinant | P1547
Biovision

Human CellExp™ Coronavirus Spike Protein (SARS-CoV-2; S1), Recombinant | P1524
Biovision

SARS Nucleocapsid protein, His Tag | NUN-S5229
Acro Biosystems

MERS Nucleocapsid protein, His Tag | NUN-M52H5
Acro Biosystems

HRP-SARS-CoV-2 Spike Trimer, His Tag | SPN-CR2H5
Acro Biosystems

HRP-SARS-CoV-2 Spike Trimer, His Tag | SPN-CR2H4
Acro Biosystems

HCoV-OC43 Nucleocapsid protein, His Tag | NUN-V5145
Acro Biosystems