Recombinant Coronavirus Nucleoprotein (CoV-NP-NL63) | P1507

Human coronavirus NL63 or HCoV-NL63 is a species of coronavirus that was identified in late 2004 in a seven-month-old child with bronchiolitis in the Netherlands. The infecting virus is an enveloped, positive-sense, single-stranded RNA virus that enters its host cell by the ACE2 receptor. Infection with the virus has been confirmed worldwide and has an association with many common symptoms and diseases. Associated diseases include mild to moderate upper respiratory tract infections, severe lower respiratory tract infection, croup and bronchiolitis. The coronavirus genome encodes a spike protein (S), an envelope protein, a membrane protein, and a nucleoprotein in this order. Nucleoprotein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. It also plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.

Biovision | P1507 | Recombinant Coronavirus Nucleoprotein (CoV-NP-NL63) DataSheet

Biomolecule/Target :

Synonyms: Nucleoprotein, Nucleocapsid protein, NC, N

Alternates names: Nucleoprotein, Nucleocapsid protein, NC, N

Taglines: Plays a role in viral assembly and subgenomic viral RNA transcription and replication

NCBI Gene ID #:

NCBI Gene Symbol: N

Gene Source: Coronavirus

Accession #: Q6Q1R8

Recombinant: False

Source: E. coli

Purity by SDS-PAGE: >95%

Assay:

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight:

Concentration:

Appearance: Sterile Filtered colorless solution

Physical form description: Liquid

Reconstitution Instructions:

Amino acid sequence: Peptide composed of 130 amino acids.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans