Recombinant Bovine Coronavirus Hemagglutinin-esterase (HE) | P1527

Structural protein that makes short spikes at the surface of the virus. It contains receptor binding and receptor-destroying activities and mediates de-O-acetylation of N-acetyl-9-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps to prevent self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. It seems to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune system.

Biovision | P1527 | Recombinant Bovine Coronavirus Hemagglutinin-esterase (HE) DataSheet

Biomolecule/Target :

Synonyms: Hemagglutinin-esterase, HE protein, E3 glycoprotein, HE

Alternates names: Hemagglutinin-esterase, HE protein, E3 glycoprotein, HE

Taglines: Structural protein that makes short spikes at the surface of the virus.

NCBI Gene ID #:

NCBI Gene Symbol: HE

Gene Source: Coronavirus

Accession #: P15776

Recombinant: TRUE

Source: Yeast

Purity by SDS-PAGE: >90%

Assay: SDS - PAGE

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 47.7 kDa (N-terminal 6xHis-tag)

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized

Reconstitution Instructions: Centrifuge the vial briefly. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Amino acid sequence: aa 19-424

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans