Recombinant 2019-nCoV NP CTD domain V2 (C-6His) | 763-PKSV030279

Recombinant 2019-nCoV NP CTD domain V2 (C-6His) | PKSV030279 | Elabscience.

Synonym: 2019-nCoVcoronavirusNPProtein;2019-nCoVnpProtein;2019-nCoVnovelcoronavirusNucleoprotein Protein

Activity: N/A

Protein Construction: Recombinant 2019-nCoV NP CTD domain is produced by our E.coli expression system and the target gene encoding Thr247-Pro364 is expressed with a 6His tag at the N-terminus.

Sequence: Thr247-Pro364

Fusion tag: C-6His

Accession: QHD43423.2

Species: SARS-CoV-2

Expressed Host: E.coli

Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.

Purity: >95% as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Mol Mass: 17.1kDa

AP Mol Mass: 17kDa

Formulation: Supplied as a 0.2 μM filtered solution of 50mM PB, 150mM NaCl, 1mM EDTA, pH 7.4

Reconstitution: Not Applicable

Background: Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may beinvolved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packagesthe positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role duringvirion assembly through its interactions with the viral genome and membrane protein M. Plays an important rolein enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of theconservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as adiagnostic tool.