Biovision | Human CellExp™ SARS-CoV-2 Spike RBD (L452R, T478K), Recombinant | P1744

Biovision | Human CellExp™ SARS-CoV-2 Spike RBD (L452R, T478K), Recombinant | P1744

Description: SARS-CoV-2 Spike protein is a large type I transmembrane protein composed of S1 subunit and S2 subunit. During viral infection, the receptor-binding domain (RBD) of the S1 subunit is responsible for the recognition and binding of host receptor ACE2, while the S2 subunit mediates viral cell membrane fusion. The SARS-CoV-2-S1-RBD/ACE2 interaction mediates viral entry into the target cells. The mutations at L452R and T478K were identified in the SARS-CoV-2 Delta (particularly B.1.617.2) variants that originated in India.

Biomolecule/Target:

Synonyms: COVID-19 Spike RBD protein; 2019-nCoV Spike RBD protein; SARS-CoV-2 Mutant (L452R, T478K)

Alternates names:

Taglines: Recombinant Spike RBD mutant of the SARS-CoV-2 Delta variant

NCBI Gene ID #: 43740568

NCBI Gene Symbol: SARS-CoV-2

Accession #: P0DTC2

Recombinant: True

Source: HEK 293 cells

Purity by SDS-PAGE: ≥ 90% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 1 EU per 1 µg of protein as determined by LAL method

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 26.6 kDa (calculated); 33-35 kDa (observed due to glycosylation)

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized powder

Reconstitution Instructions:

Amino acid sequence:

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans