Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (Trehalose free) | S1N-M12A1

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SKU:
S1N-M12A1
Epitope:
Spike RBD
Isotype:
Human IgG1
Source:
Mouse
£395.60 - £232,243.00
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Description

Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (Trehalose free) | S1N-M12A1 | Acro Biosystems | SARS-CoV-2 Antibodies For Diagnostic

Source
 
Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2) . 
 
Isotype
 
Human IgG1/kappa
 
Specificity
 
This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. No cross-reactivity is detected with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.
 
Application
 
This antibody can be paired with other Anti-SARS-CoV-2 Spike S1 antibodies to detect SARS-CoV-2 Spike S1 protein in sandwich ELISA or LFA assay.
 
Purity

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

Formulation

Supplied as 0.2 μm filtered solution in PBS, pH7.4 .

Contact us for customized product form or formulation.

Storage

 

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

For long term storage, the product is stable for up to 3 years at -70°C from date of receipt;

For short term storage, the product is stable for up to 12 months at 2-8°C from date of receipt.

Shipping
This product is supplied and shipped as sterile liquid solution with dry ice, please inquire the shipping cost.
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